بررسی تاثیر مصرف جوانهی گندم بر پروفایل لیپید

Authors

  • آسایی, عصمت
  • سرشار, نرگس
  • مختاریان دلویی, حسین
  • مشکی, مهدی
  • یعقوبی اول ریابی, مهدی
Abstract:

diseases and emphasis on using nondrug treatments, this study was performed to assess the effect of wheat germ on lipid profile reduction among hyperlipidemia and normolipidomia students. Materials and Methods: 108 volunteer students in the age range of 21.33±2.15 years old (74 normolipidemics, 34 hyperlipidemics) were entered to the study. In addition to their typical diet, these students were asked to take a 30- gram wheat germ in their daily diet for 4 weeks. Hyperlipidemia and normolipidomia participants were determined based on National Cholesterol Education Program Adult Treatment Panel 3 (NCEPATP3) guidelines. Anthropometric and metabolic measurements, calorie and mineral intakes, before and after the intervention were taken and analyzed using paired t-test (SPSS version 19). Results: In the wheat germ group, total cholesterol, triglycerides and VLDL (p=0.001) significantly reduced to 10.5, 19 and 20%, respectively. Also parameters of HDL-C/TC (p=0.004) and systolic blood pressure (p=0.046) significantly increased (in both groups) and decreased (in hyper lipidemic group), respectively. In addition, total cholesterol level decreased significantly (p=0.003) in normolipidemic students. There was no statistically significant change in other parameters. Conclusion: Due to significant decrease in triglycerides in hyperlipidemic group and total cholesterol levels in both groups, consumption of wheat germ, as a nondrug treatment, for prevention of cardiovascular diseases and dyslipidemia is suggested. References 1- Nasir A, Shah H. Assessment of cardiovascular disease risk factors among school children in private schools in Karachi, Pakistan: A pilot study. J Obes Wt Loss Ther. 2012 2: 1-4. 2- Namazi MH, Mohagheghi A, Ostevaneh MR. Prevention of cardiovascular diseases in developing countries. Arch Iran Med. 2012 15: 528-530. 3- Sun S, Xu H, Ngeh L. 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Preventive effect of wheat germ on hypercholesteremic and atherosclerosis in rats fed cholesterol-containing diet. Pak J Nutr. 2011 10: 424-32. 11- Alessandri C, Pignatelli P, Loffredo L, et al. Alpha linolenic acid rich wheat germ oil decreases oxidative stress and CD40 ligand in patiens whit mild hypercholesterolemia. Arteriosclerosis, thrombosis and vascular biology. 2006 26: 2577-2578. 12- Nounou HA, Deif MM, Shalaby MA. Effect of flaxseed supplementation and exercise training on lipid profile, oxidative stress and inflammation in rats with mycocardial ischemia. Lipids Health Dis. 2012 11: 129. 13- Ammar ASM. Effect of wheat germ addition on physicochemical and antioxidant properties of data syrup. Int J Food Sci Technol. 2012 7: 486-97. 14- Zhu KX, Zhou HM, Qian HF. Proteins extracted from defatted wheat germ: nutritional and structural properties. Cereal chemistry J. 2012 83: 69-75. 15- lin X, Racette SB, Lefevre M, et al. Combined effect of enzetimibe and phytosterols on cholesterol metabolism: a randomazmized control feeding study in humans. Circulation. 2012 124: 596-601. 16- Racette SB, nLina X, Leferve A, et al. Dose effect of dietary phytosterols on cholesterol metabolism :a control feeding study. J Clin Nutr. 2010 91: 32-38. 17- Haripriya S, Prmakumaria S. Beta sistosterol of wheat germ reduceds blood glucose in human. J Life Sci. 2010 2: 87-92. 18- Kan A. Chemical and elemental characterization of wheat germ oil (triticum spp.l.) cultivated in Turkey. Afr J Agric Res. 2012 7: 4979-4982. 19- Mueller T, Voigt W. Fermented wheat germ extera nutritional supplement or anticancer drug? Nutr J. 2011 10: 114-129. 20- Judson PL, Sawah EA, Marchion M, et al. Characterizing the efficacy of fermented wheat germ extra against ovarian cancer and defining the genomic basis of its activity. Int J Gynecol Cancer. 2012 22: 960-67. 21- Zakeri HR, Ataie Jafari A, Rajabi M, Hosseini S. 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Journal title

volume 23  issue 98

pages  112- 121

publication date 2015-05

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